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  1. Week 7: reading group “Revisiting the Classics”
  2. Reading group closing survey
  3. Recruiting: A podcast audio editor!

1. Week 7: reading group “Revisiting the Classics”

The reading group “revisiting the classics” is inspired by the special panel session at DNA28, ‘A tribute to Ned Seeman’. We heard how Ned’s paper influenced other researchers, and later development of the DNA Nanotechnology field. Prof. Hao Yan commented that there are a lot of foundational knowledge and interesting ideas in Ned’s early papers. We are currently running a reading group to read seven of Ned Seeman’s papers over seven weeks.

On week 7, we are going to discuss “T.-J. Fu and N.C. Seeman, DNA Double Crossover Structures, Biochemistry 32, 3211-3220 (1993)]”. Please come with thoughts/questions/ideas/whatever in mind, and we will have a gathering and discussion session!

We will have 2 groups. Please pick the one that works for you and register by contacting us.

If there is any question about a specific group (content, zoom link, etc.), feel free to contact the organizers leading that group.

Note that seats will be limited so please sign up as soon as you can! If you later realize that you cannot attend after registering, we kindly ask that please modify your answer. Meeting information (e.g. zoom links) will be sent later to attendees.

Below are the papers for these 7 weeks (list suggested by Prof. Hao Yan):

  1. N.C. Seeman, Nucleic Acid Junctions and Lattices. Journal of Theoretical Biology 99, 237-247 (1982).
  2. B.H. Robinson and N.C. Seeman, The Design of a Biochip: A Self-Assembling Molecular-Scale Memory Device. Protein Engineering 1, 295-300 (1987).
  3. N.C. Seeman, Physical Models for Exploring DNA Topology. Journal of Biomolecular Structure and Dynamics 5, 997-1004 (1988).
  4. N.C. Seeman, De Novo Design of Sequences for Nucleic Acid Structure Engineering, Journal of Biomolecular Structure and Dynamics 8, 573-581 (1990).
  5. S.M. Du, S. Zhang and N.C. Seeman, DNA Junctions, Antijunctions and Mesojunctions, Biochemistry 31, 10955-10963 (1992).
  6. N.C. Seeman, J. Chen, S.M. Du, J.E. Mueller, Y. Zhang, T.-J. Fu, H. Wang, Y. Wang, and S. Zhang, Synthetic DNA Knots and Catenanes, New Journal of Chemistry 17, 739-755 (1993).
  7. T.-J. Fu and N.C. Seeman, DNA Double Crossover Structures, Biochemistry 32, 3211-3220 (1993)

2. Reading group closing survey

During the seven weeks’ journey reading Ned Seeman’s classic papers, we traveled from the very early idea of DNA immobile junctions to the exploration of different kinds of junctions, and how to engineer these DNA junctions, and how the DNA structures can be potentially used for “crazy” applications. As the reading group comes closer to an end, it would be great to gather some feedback and thoughts from you for future events. If you would like to tell us anything (such as vote on your favorite paper, suggest themes or ideas for future reading groups, etc.), please fill in this survey.

3. Recruiting: A podcast audio editor!

Are you skilled with audio editing software, enjoy the podcast, and want to help make it even better? Then please get in touch!

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